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Fig. 6 | BMC Medical Genomics

Fig. 6

From: Identification of the ferroptosis-related long non-coding RNAs signature to improve the prognosis prediction and immunotherapy response in patients with NSCLC

Fig. 6

Construction of the FRGs-lncRNAs signature in the training group. (A) Lasso coefficients profiles of the 10 FRGs-lncRNAs. (B) Lasso regression analysis obtained 9 prognostic FRGs-lncRNAs. Distribution (C) and survival status plot (D) of NSCLC patients based on the median risk score. Kaplan–Meier survival (E) and ROC curve analysis (F) of the FRGs-lncRNAs signature in the training group. (G) Heatmap of the expression profiles of the FRGs-lncRNAs in low- and high-risk groups. Each curve in A represents the changing track of Lasso’s coefficients of the 10 prognosis-related FRGs-lncRNAs, respectively. The Y-axis represents the Lasso’s coefficient, the lower and upper X-axis represents log(λ), and the number of FRGs-lncRNAs with non-zero coefficients, respectively. In B, the Y-axis represents partial likelihood deviance, the lower and upper X-axis represents log(λ) and the number of FRGs-lncRNAs corresponding to the different log(λ), respectively. The upper X-axis corresponding to the smallest partial likelihood deviance is the best number of FRGs-lncRNAs included in the model. NSCLC, non-small cell lung cancer; lncRNAs: long non-coding RNAs; FRGs, ferroptosis-related genes; FRGs-lncRNAs: FRGs related lncRNAs; ROC, receiver operating characteristic

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