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Table 2 The top 10 hypermethylated genes in tumor tissues

From: Comparison of tumor and two types of paratumoral tissues highlighted epigenetic regulation of transcription during field cancerization in non-small cell lung cancer

Gene

log2(Fold change)

p value

Adjusted p value

BARHL2

0.486

2.42E − 15

1.55E − 12

MIR124-3

0.408

4.31E − 09

7.68E − 08

DMRTA2

0.337

1.60E − 16

1.48E − 13

ESPN

0.330

3.32E − 11

1.63E − 09

OTX2

0.322

1.14E − 15

8.60E − 13

YAE1D1

0.316

2.83E − 13

4.90E − 11

SKOR1

0.313

5.53E − 16

4.60E − 13

ZNF876P

0.310

4.89E − 14

1.45E − 11

HOXA9

0.305

3.57E − 12

2.85E − 10

OTX1

0.305

9.17E − 14

2.12E − 11