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Table 4 PCA of the methylation levels of field cancerization-specific DMRs in tumor samples revealed significant associations (in bold) with some clinical features

From: Comparison of tumor and two types of paratumoral tissues highlighted epigenetic regulation of transcription during field cancerization in non-small cell lung cancer

P value

PC1

PC2

PC3

Age

0.007

1.081e − 13

3.091e − 05

Sex

0.374

0.1621

0.0026

T-stage

0.1714

0.9696

0.054

N-stage

0.2857

0.2769

0.9209

Histology

0.0728

0.0003

0.0792

Smoking status

0.2904

0.7241

0.3701

Tumor size

0

0.223

0

  1. ADJ—tumor-adjacent normal tissue, DIS—tumor-distant normal tissue, DMR—differential methylation region, TUM—surgically-resected tumor
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BMC Medical Genomics

ISSN: 1755-8794

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