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Table 4 PCA of the methylation levels of field cancerization-specific DMRs in tumor samples revealed significant associations (in bold) with some clinical features

From: Comparison of tumor and two types of paratumoral tissues highlighted epigenetic regulation of transcription during field cancerization in non-small cell lung cancer

P value PC1 PC2 PC3
Age 0.007 1.081e − 13 3.091e − 05
Sex 0.374 0.1621 0.0026
T-stage 0.1714 0.9696 0.054
N-stage 0.2857 0.2769 0.9209
Histology 0.0728 0.0003 0.0792
Smoking status 0.2904 0.7241 0.3701
Tumor size 0 0.223 0
  1. ADJ—tumor-adjacent normal tissue, DIS—tumor-distant normal tissue, DMR—differential methylation region, TUM—surgically-resected tumor