Table 3 Genotype and allele frequencies of the studied polymorphisms in patients and healthy control

CATSPER1 (rs2845570)

Codominant

GG

81 (81%)

98 (98%)

Ref

Ref = 1

GT

14 (14%)

2 (2%)

0.001*

8.47 (2.14–38.1)

TT

5 (5%)

0 (0%)

0.021*

Infinity (1.7–infinity)

Dominant

GG

81 (81%)

98 (98%)

Ref

Ref = 1

GT + GG

19 (19%)

2 (2%)

0.0001*

11.49 (2.8–50.7)

Recessive

TT

5 (5%)

0 (0%)

Ref

Ref = 1

GT + GG

95 (95%)

100 (100%)

0.059

Infinity (1.5–infinity)

Overdominant

GT

14 (14%)

2 (2%)

Ref

Ref = 1

GG + TT

86 (86%)

98 (98%)

0.0029*

7.97 (2.02–35.8)

Alleles

G wild

176 (88%)

198 (99%)

Ref

Ref = 1

T mutant

24 (12%)

2 (1%)

0.0001*

13.5 (3.6–58.4)

SPATA16 (rs1515442)

Codominant

TT

87 (87%)

96 (96%)

Ref

Ref = 1

TC

12 (12%)

4 (4%)

0.039*

3.31 (1.01–9.61)

CC

1 (1%)

0 (0%)

0.478

Infinity (0.12–infinity)

Dominant

TT

87 (87%)

96 (96%)

Ref

Ref = 1

TC + CC

13 (13%)

4 (4%)

0.039*

3.58 (1.14–10.3)

Recessive

CC

1 (1%)

0 (1%)

Ref

Ref = 1

TC + TT

99 (99%)

100 (100%)

 > 0.999

Infinity (0.11–infinity)

Overdominant

TC

12 (12%)

4 (4%)

Ref

Ref = 1

CC + TT

88 (88%)

96 (96%)

0.065

3.27 (1.0–9.5)

Alleles

T wild

186 (93%)

196 (98%)

Ref

Ref = 1

C mutant

14 (7%)

4 (2%)

0.016*

3.69 (1.2–10.4)

TEX11 (rs143246552)

Codominant

TT

95 (95%)

98 (98%)

Ref

Ref = 1

TC

2 (2%)

2 (2%)

0.999

1.03 (0.815–6.7)

CC

3 (3%)

0 (0%)

0.246

Infinity (0.87–infinity)

Dominant

TT

95 (95%)

98 (98%)

Ref

Ref = 1

TC + CC

5 (5%)

2 (2%)

0.444

2.58 (0.53–13.1)

Recessive

CC

3 (3%)

0 (0%)

Ref

Ref = 1

TC + TT

97 (97%)

100 (100%)

0.246

Infinity (0.87–infinity)

Overdominant

TC

2 (2%)

2 (2%)

Ref

Ref = 1

CC + TT

98 (98%)

98 (98%)

1

1 (0.15–6.48)

Alleles

T wild

192 (96%)

198 (99%)

Ref

Ref = 1

C mutant

8 (4%)

2 (1%)

0.055

4.12 (1.0–19.4)