Skip to main content

Table 1 VKORC1 haplotypes in different world populations

From: Cross-ethnic analysis of common gene variants in hemostasis show lopsided representation of global populations in genetic databases

Gene VKORC1 Haplotype frequencies
Cromosome 16 16 16 16 16 16 16 16 This study 1000 genomes phase III
Position hg19 31,102,321 31,103,796 31,104,509 31,104,720 31,104,878 31,105,353 31,105,554 31,105,945
Ref. allele C A C C G G A C
Alt. Allelle T G G T A A C A
rs-number rs7294 rs2359612 rs8050894 rs72547529 rs9934438 rs17708472 rs2884737 rs61742245 SOM ASW CEU CHB GIH JPT LWK MXL TSI YRI
Haplotypes C A C C G G A C   7%      12%    14%
C A C T G G A C        3%    
C A G C A G A C 3% 8% 17% 95% 11% 90% 3% 33% 15% 3%
C A G C A G C C 41% 7% 28%   7%    14% 33%  
C G C C G A A C 14% 7% 26%   16%   6% 15% 16% 2%
C G C C G G A A 8%          
C G C C G G A C 1% 8%      19%    10%
C G G C G G A C   15%      13% 3% 2% 19%
T G C C G G A C 31% 48% 32% 4% 67% 10% 43% 34% 33% 51%
  1. The following populations were included: Somali in Northeastern Somalia (SOM), African Ancestry in Southwest USA (ASW), Northern Europeans from Utah (CEU), Han Chinese in Beijing, China (CHB), Gujarati Indians in Houston, Texas, USA (GIH), Japanese in Tokyo, Japan (JPT), Luhya in Webuye, Kenya (LWK), Mexican Ancestry in Los Angeles, CA, USA (MXL), Toscani in Italy (TSI), and Yoruba in Ibadan, Nigeria (YRI)