Fig. 4

Allele frequency and concordance rate between the two panels. A The distribution of allele frequency of variants detected only in the tumor-only (TO) panel and those detected in both panels. B The distribution of mean allele frequency of variants reported by the TO panel and/or tumor–normal (TN) panels in Group FF (pastel pink dots), FFPE-H (blue dots), and FFPE-L (green dots). The vertical axis shows the mean allele frequency in logarithmic scale. The horizontal red line and blue line indicate a frequency of 5% and 15%, respectively. C The distribution of allele frequency of variants detected only in the TN panel and those detected in both panels