Association of the tissue infiltrated and peripheral blood immune cell subsets with response to radiotherapy for rectal cancer

Table 1 Significant differential proportions of tumor immune/stromal cell types between the non-responsive and responsive rectal cancer tissues

Cell types	Methods	(R) Mean ± SD	(NR) Mean ± SD	p value	Variance type
CD4⁺ cells	TIMER	0.1378 ± 0.0368	0.1071 ± 0.0373	0.0215	Equal
CD8⁺ cells	TIMER	0.1798 ± 0.0217	0.2104 ± 0.0415	0.0239	Equal
				0.0031	Unequal
CD4⁺/CD8⁺ ratio	TIMER	0.7869 ± 0.2696	0.5564 ± 0.2813	0.0210	Equal
Preadipocytes	xCell	0.0129 ± 0.0195	0.0363 ± 0.0286	0.0154	Equal
Adipocytes	xCell	0.0479 ± 0.0249	0.0314 ± 0.0230	0.0210	Equal
T cells CD4 memory resting	CIBERSORT	0.0864 ± 0.1149	0.0293 ± 0.0583	0.0330	Equal
Macrophages M2	CIBERSORT	0.0144 ± 0.0199	0.0346 ± 0.0380	0.0280	Unequal

SD: standard deviation; (R): propotion of respornsive; (NR): proportion of non-respondive

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