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Table 1 Top 3 terms of GO and top 2 terms of KEGG pathway functional enrichment analysis of each category

From: Identification of hub genes and regulatory networks in histologically unstable carotid atherosclerotic plaque by bioinformatics analysis

Category

Term

Log P

Count

Hub genes

GO CCs

GO:0062023: collagen-containing extracellular matrix

− 15.26

19

C1QC, FMOD

GO CCs

GO:0005925: focal adhesion

− 9.64

14

HCK, LCP1, RAC2

GO CCs

GO:0032432: actin filament bundle

− 9.51

8

LCP1, MYH10, PLS3, TPM1

GO BPs

GO:0030198: extracellular matrix organization

− 9.8

12

FMOD, LCP1

GO BPs

GO:0050900: leukocyte migration

− 8.05

10

FCER1G, HCK

GO BPs

GO:0003013: circulatory system process

− 7.76

13

TPM1

GO MFs

GO:0005201: extracellular matrix structural constituent

− 9.3

10

FMOD

GO MFs

GO:0003779: actin binding

− 8.35

13

LCP1, MYH10, PLS3, TPM1

GO MFs

GO:0005509: calcium ion binding

− 6.73

14

LCP1, PLS3

KEGG

hsa04062: Chemokine signaling pathway

− 4.24

6

HCK, RAC2

KEGG

hsa04810: Regulation of actin cytoskeleton

− 4

6

MYH10, RAC2

  1. GO Gene Ontology, KEGG Kyoto Encyclopedia of Genes and Genomes, CC Cellular compartment, BP Biological processes, MF Molecular function