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Fig. 1 | BMC Medical Genomics

Fig. 1

From: Integrated investigation of DNA methylation, gene expression and immune cell population revealed immune cell infiltration associated with atherosclerotic plaque formation

Fig. 1

Analysis of the hypermethylated genes previously identified in atherosclerotic aortas and carotid plaques. (A) Workflow diagram showing the exploration pipeline. (B) Principal component analysis (PCA) of atherosclerotic plaque vs non-atherosclerotic aortic vascular samples based on DNA methylation level. The samples were grouped by disease state and the ellipse for each group is the confidence ellipse. Confidence interval is 0.95. (C) Bar plot showing the top 10 most enriched GO terms of differential methylated genes (DMGs). (D) Heatmap showing the DNA methylation level of DMGs involved in cell adhesion and blood coagulation

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