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Fig. 2 | BMC Medical Genomics

Fig. 2

From: Integrated investigation of DNA methylation, gene expression and immune cell population revealed immune cell infiltration associated with atherosclerotic plaque formation

Fig. 2

Transcriptome analysis of deregulated gene expression in atherosclerotic carotid plaques. (A) Principal component analysis (PCA) of atherosclerotic carotid plaque vs. PBMCs samples based on gene expression level. The samples were grouped by disease state. The ellipse for each group is the confidence ellipse. Confidence interval is 0.95. (B) The same with A but for ATH vs. MIT samples. (C) Expression heatmap of all differentially expressed genes between plaque vs. PBMCs. (D–E) The top 10 most enriched GO terms of down-regulated (D) and up-regulated (E) genes from differential expressed genes between plaque vs. PBMCs. (F–G). The top 10 most enriched GO terms of up-regulated (F) and down-regulated (G) genes from differential expressed genes between ATH vs. MIT

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BMC Medical Genomics

ISSN: 1755-8794

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