Table 2 Comparison of the quality control metrics of four groups with different level of hemolysis
From: The effect of hemolysis on quality control metrics for noninvasive prenatal testing
| Quality control metric | Group I | Group II | Group III | Group IV |
|---|---|---|---|---|
| Library concentration (ng/μL) | 9.69 |
11.25 P = 0.218 |
10.94 P = 0.302 |
7.30 P = 0.036 |
| Fetal fraction (%) | 16.45 |
15.71 P = 0.382 |
15.66 P = 0.694 |
21.13 P = 0.002 |
| GC content (%) | 40.69 |
40.70 P = 0.840 |
40.68 P = 0.947 |
40.68 P = 0.768 |
| Mapping rate (%) | 75.96 |
75.96 P = 0.976 |
75.87 P = 0.448 |
75.79 P = 0.728 |
| Duplication rate (%) | 9.40 |
8.49 P = 0.187 |
7.89 P = 0.132 |
12.91 P = 0.034 |