Table 2 Comparison of the quality control metrics of four groups with different level of hemolysis
From: The effect of hemolysis on quality control metrics for noninvasive prenatal testing
Quality control metric | Group I | Group II | Group III | Group IV |
|---|---|---|---|---|
Library concentration (ng/μL) | 9.69 | 11.25 P = 0.218 | 10.94 P = 0.302 | 7.30 P = 0.036 |
Fetal fraction (%) | 16.45 | 15.71 P = 0.382 | 15.66 P = 0.694 | 21.13 P = 0.002 |
GC content (%) | 40.69 | 40.70 P = 0.840 | 40.68 P = 0.947 | 40.68 P = 0.768 |
Mapping rate (%) | 75.96 | 75.96 P = 0.976 | 75.87 P = 0.448 | 75.79 P = 0.728 |
Duplication rate (%) | 9.40 | 8.49 P = 0.187 | 7.89 P = 0.132 | 12.91 P = 0.034 |