Fig. 1
From: Somatic targeted mutation profiling of colorectal cancer precursor lesions
Waterfall plot of the driver mutation spectrum of colorectal cancer precursor lesions. Plots show the frequency of samples mutated for adenoma lesions (a) and serrated polyps (b). The upper panel demonstrates the frequency of mutation for each sample. Left panel shows the frequency of samples harboring mutations according to the gene. The lower panel indicates the lesion site and classification of the lesion. Adenomas are more likely to harbor mutations in APC while serrated polyps frequently harbor BRAF mutations. HP: hyperplastic polyp; SSL: sessile serrated lesion