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Table 4 Allele and genotype frequencies of IL2RA in CP with spastic tetraplegia and controls

From: An association study of IL2RA polymorphisms with cerebral palsy in a Chinese population

Group

Allele frequency

P value

OR [95% CI]

Genotype frequency

P value

rs12244380

A

G

A/A

A/G

G/G

CP

456 (0.857)

76 (0.143)

0.716

0.948 [0.713–1.262]

198 (0.744)

60 (0.226)

8 (0.030)

0.298

Control

1240 (0.864)

196 (0.136)

533 (0.742)

174 (0.242)

11 (0.015)

rs2025345

A

G

0.177

0.868 [0.707–1.066]

A/A

A/G

G/G

0.0097a

CP

324 (0.611)

206 (0.389)

88 (0.332)

148 (0.558)

29 (0.109)

Control

915 (0.644)

505 (0.356)

298 (0.420)

319 (0.449)

93 (0.131)

rs12722561

C

T

0.053

1.354 [0.995–1.844]

C/C

C/T

T/T

0.137

CP

487 (0.892)

59 (0.108)

216 (0.791)

55 (0.201)

2 (0.007)

Control

1225 (0.859)

201 (0.141)

525 (0.736)

175 (0.245)

13 (0.018)

rs4749926

A

G

0.389

1.091 [0.894–1.332]

A/A

A/G

G/G

0.540

CP

227 (0.416)

319 (0.584)

40 (0.147)

147 (0.538)

86 (0.315)

Control

592 (0.395)

908 (0.605)

106 (0.141)

380 (0.507)

264 (0.352)

rs2104286

C

T

0.633

0.931 [0.696–1.247]

C/C

C/T

T/T

0.551

CP

70 (0.126)

484 (0.874)

1 (0.004)

68 (0.245)

208 (0.751)

Control

200 (0.134)

1288 (0.866)

8 (0.011)

184 (0.247)

552 (0.742)

  1. P value after Bonfferoni a: 0.048