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Table 6 Allele and genotype frequencies of IL2RA in CP with pregnancy-induced hypertension and controls

From: An association study of IL2RA polymorphisms with cerebral palsy in a Chinese population

Group

Allele frequency

P value

OR [95% CI]

Genotype frequency

P value

rs12244380

A

G

A/A

A/G

G/G

CP

37 (0.771)

11 (0.229)

0.068

0.531 [0.266–1.059]

16 (0.667)

5 (0.208)

3 (0.125)

0.0005a

Control

1240 (0.864)

196 (0.136)

533 (0.742)

174 (0.242)

11 (0.015)

rs2025345

A

G

0.783

0.920 [0.0.508–1.667]

A/A

A/G

G/G

0.418

CP

30 (0.625)

18 (0.375)

8 (0.333)

14 (0.583)

2 (0.083)

Control

915 (0.644)

505 (0.356)

298 (0.420)

319 (0.449)

93 (0.131)

rs12722561

C

T

0.087

0.552 [0.277–1.100]

C/C

C/T

T/T

0.066

CP

37 (0.771)

11 (0.229)

15 (0.625)

7 (0.292)

2 (0.083)

Control

1225 (0.859)

201 (0.141)

525 (0.736)

175 (0.245)

13 (0.018)

rs4749926

A

G

0.519

1.205 [0.683–2.127]

A/A

A/G

G/G

0.710

CP

22 (0.440)

28 (0.560)

5 (0.200)

12 (0.480)

8 (0.320)

Control

592 (0.395)

908 (0.605)

106 (0.141)

380 (0.507)

264 (0.352)

rs2104286

C

T

0.520

1.288 [0.594–2.792]

C/C

C/T

T/T

0.570

CP

8 (0.167)

40 (0.833)

0 (0.000)

8 (0.333)

16 (0.667)

Control

200 (0.134)

1288 (0.866)

8 (0.011)

184 (0.247)

552 (0.742)

  1. P value after Bonfferoni: a: 0.0026