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Fig. 5 | BMC Medical Genomics

Fig. 5

From: An asparagine metabolism-based classification reveals the metabolic and immune heterogeneity of hepatocellular carcinoma

Fig. 5

DNA damage response pathway in the two subgroups and relative drug sensitivity analyses of HCC in the TCGA database. A The expressions of representative genes of DNA damage response pathway in high asparagine metabolism HCC subgroup were significantly higher than the low asparagine metabolism group. B The IC50 of two subgroups in response to sorafenib showed no difference. C The IC50 of high asparagine metabolism subgroup in response to CHEK1 inhibitor AZD7762 and PARP 1/2 inhibitor ABT-888 were lower than the low asparagine metabolism subgroup

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BMC Medical Genomics

ISSN: 1755-8794

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