Genes related to allergen exposure in allergic rhinitis: a gene-chip-based study in a mouse model

Table 1 Top 21 genes with higher degrees identified by gene co-expression network analysis

Gene	Description	Clustering coefficient	Degree	k-core
BCL3	B cell leukemia/lymphoma 3	0.37687688	37	11
CSF2RB2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte–macrophage)	0.33492063	36	11
HNRNPA3	heterogeneous nuclear ribonucleoprotein A3	0.19663866	35	11
SBNO2	strawberry notch homolog 2 (Drosophila)	0.43225806	31	11
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100	0.43678161	30	11
FABP5	fatty acid binding protein 5, epidermal	0.47883598	28	11
RPL38	ribosomal protein L38	0.3048433	27	11
SLC6A14	solute carrier family 6 (neurotransmitter transporter), member 14	0.44159544	27	11
SPRR2A1	small proline-rich protein 2A1	0.31339031	27	11
CISH	cytokine inducible SH2-containing protein	0.43384615	26	11
MS4A6D	membrane-spanning 4-domains, subfamily A, member 6D	0.51076923	26	11
SOCS3	suppressor of cytokine signaling 3	0.49538462	26	11
CD53	CD53 antigen	0.42333333	25	11
ENTPD3	ectonucleoside triphosphate diphosphohydrolase 3	0.52666667	25	11
BHLHE40	basic helix-loop-helix family, member e40	0.37681159	24	11
CLDN4	claudin 4	0.43478261	24	11
OSMR	oncostatin M receptor	0.40942029	24	11
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.45289855	24	11
TNIP3	TNFAIP3 interacting protein 3	0.4673913	24	11
TREM1	triggering receptor expressed on myeloid cells 1	0.55434783	24	11
ZC3H12A	zinc finger CCCH type containing 12A	0.48188406	24	11

ISSN: 1755-8794