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Fig. 5 | BMC Medical Genomics

Fig. 5

From: MiRNA/mRNA network topology in hepatitis virus B-related liver cirrhosis reveals miR-20a-5p/340-5p as hubs initiating fibrosis

Fig. 5

Transfection of miRNA mimics of the two hub miRNAs. (A) Transfection with miR-20a-5p and miR-340-5p mimics in THP-1 cells. (B) Transfection with miR-20a-5p and miR-340-5p mimics in LX-2 cells. The inhibitor and transfection reagent groups were used as the negative controls. The expression levels of miR-20a-5p and miR-340-5p were measured using a TaqMan assay after transfection. Numbers of replicates in each group for qRT-PCR (n = 5 in the MIMICS, INHIBITOR, TRANS and NC groups, respectively), NC Normal control, TRANS Transfection. **p < 0.001

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