Table 2 Association between CYP4V2 polymorphisms and IS risk

rs1398007

Codominant

C/C

272 (47.3%)

242 (42.1%)

1

1596.7

1632

T/C

250 (43.5%)

298 (51.8%)

1.34 (1.05–1.71)

T/T

53 (9.2%)

35 (6.1%)

0.76 (0.48–1.20)

Dominant

C/C

272 (47.3%)

242 (42.1%)

1

1600.7

1631

T/C-T/T

303 (52.7%)

333 (57.9%)

1.24 (0.98–1.56)

Log-additive

–

–

–

1.06 (0.88–1.28)

1603.6

1633.9

rs13146272

Codominant

C/C

228 (39.8%)

229 (39.8%)

1

1602.4

1637.7

 C/A

268 (46.8%)

259 (45%)

0.96 (0.74–1.23)

A/A

77 (13.4%)

87 (15.1%)

1.11 (0.78–1.59)

Dominant

C/C

228 (39.8%)

229 (39.8%)

1

1601.1

1631.4

 C/A-A/A

345 (60.2%)

346 (60.2%)

0.99 (0.78–1.26)

Log-additive

–

–

–

1.03 (0.87–1.22)

1601

1631.3

rs3736455

Codominant

T/T

207 (36.1%)

201 (35%)

1

1601.4

1636.7

G/T

292 (51%)

283 (49.2%)

1.00 (0.77–1.29)

G/G

74 (12.9%)

91 (15.8%)

1.26 (0.87–1.81)

Dominant

T/T

207 (36.1%)

201 (35%)

1

1601

1631.3

G/T-G/G

366 (63.9%)

374 (65%)

1.05 (0.82–1.34)

Log-additive

–

–

–

1.09 (0.92–1.29)

1600.2

1630.5

rs1053094

Codominant

T/T

245 (42.8%)

228 (39.6%)

1

1602

1637.3

T/A

263 (45.9%)

278 (48.4%)

1.14 (0.89–1.46)

A/A

65 (11.3%)

69 (12%)

1.16 (0.79–1.71)

Dominant

T/T

245 (42.8%)

228 (39.6%)

1

1600

1630.2

T/A-A/A

328 (57.2%)

347 (60.4%)

1.14 (0.90–1.45)

Log-additive

–

–

–

1.10 (0.92–1.31)

1600.1

1630.4

rs56413992

Codominant

C/C

369 (64.3%)

359 (62.5%)

1

1602.5

1637.9

T/C

182 (31.7%)

190 (33.1%)

1.07 (0.83–1.38)

T/T

23 (4%)

25 (4.4%)

1.17 (0.65–2.11)

Dominant

C/C

369 (64.3%)

359 (62.5%)

1

1600.6

1630.9

T/C-T/T

205 (35.7%)

215 (37.5%)

1.08 (0.85–1.38)

Log-additive

–

–

–

1.08 (0.88–1.32)

1600.5

1630.8