Fig. 8

The mutation profile and TMB in the low- and high-risk groups. A waterfall plot of the top 20 most mutated genes in different patients shows the relationship with gender and MYCN status. B Counting mutations in seven common classifications, separately. C–D Waterfall plot of top 10 mutated genes in MYCN-related DEIRGs between the two risk groups. E Boxplot and F correlation graphs indicated the difference in TMB in the two risk score groups