Fig. 2

Screening pyroptosis-related prognostic genes and constructing a prognostic signature model. A Venn diagram of DEGs and prognostic genes. B The heatmap of candidate genes expression. C Forest plots showed the univariate Cox regression analysis of the candidate genes. D The PPI network of the candidate genes. E Gene correlation networks of candidate genes. Red color means a positive correlation, blue color means a negative correlation. F Selection of the penalty parameter (λ) in the LASSO model by tenfold cross-validation. The lower x-coordinate is the value of Log(λ), the upper x-coordinate is the number of candidate genes, and the dashed line is the number of candidate genes corresponding to the cutoff value of Log(λ). G LASSO coefficient profiles of the expression of 21 candidate genes