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Fig. 7 | BMC Medical Genomics

Fig. 7

From: Three nervous system-specific expressed genes are potential biomarkers for the diagnosis of sporadic amyotrophic lateral sclerosis through a bioinformatic analysis

Fig. 7

ROC curve and prognosis prediction ability of 5 nervous system-specific expressed hub genes in sALS samples. AE ROC curve of 5 nervous system-specific expressed hub genes were constructed by GSE112681 dataset. The AUC of these genes was 0.832 for AKT1, 0.811 for APP, 0.927 for LRRK2, 0.832 for PSEN1, and 0.810 for SLCO1A2. FJ survival analysis show that high expression of these genes predicted poor prognosis for sALS. FJ survival analysis based on hub genes expression by Kaplan–Meier method

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