From: Whole-exome sequencing identified recurrent and novel variants in benzene-induced leukemia
Variables | Total (n = 10) | Clinical diagnosis | |
---|---|---|---|
AML (n = 4) | CML (n = 6) | ||
Age [year, mean (SE)] | 44.00 (1.69) | 44.25 (3.01) | 43.83 (2.21) |
Gender [male (%)] | 30.00 | 25.00 | 33.33 |
Race [Han (%)] | 100.00 | 100.00 | 100.00 |
Smoking [yes (%)] | 10.00 | 25.00 | 0 |
Drinking [yes (%)] | 10.00 | 25.00 | 0 |
Benzene exposure duration [year, mean (SE)] | 6.47 (1.13) | 7.93 (1.92) | 5.74 (1.46) |
White blood cell count [× 109/L, mean (SE)] | 4.77 (0.68) | 6.50 (1.20) | 3.62 (0.41) |
Neutrophil count [× 109/L, mean (SE)] | 2.76 (0.53) | 3.95 (1.05) | 1.97 (0.28) |
Platelet count [× 109/L, mean (SE)] | 187.90 (24.95) | 208.25 (52.69) | 174.33 (25.79) |
Immature granulocyte percentage [%, mean (SE)] | 0.17 (0.05) | 0.12 (0.08) | 0.20 (0.08) |
BCR-ABL1 fusion gene [positive (%)] | 60.00 | 0 | 100.00 |
Treatment | Â | Â | Â |
 Chemotherapy (%) | 40.00 | 100.00 | 0 |
 TKIs therapy (%) | 60.00 | 0 | 100.00 |
Survival time [year, mean (SE)] | 8.56 (0.66) | 7.52 (0.62) | 9.24 (0.96) |