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Table 8 Summary of SNP-SNP interactions on the risk of thyroid cancer analyzed by MDR method

From: Variants in TPO rs2048722, PTCSC2 rs925489 and SEMA4G rs4919510 affect thyroid carcinoma susceptibility risk

Model

Bal.Acc.CV training

Bal.Acc.CV testing

CV consistency

OR (95% CI)

p

rs925489

0.536

0.484

5/10

1.513 (1.048–2.183)

0.026*

rs925489, rs4919510

0.557

0.501

7/10

1.577 (1.176–2.114)

0.002*

rs2048722, rs925489, rs4919510

0.567

0.499

10/10

1.666 (1.242–2.235)

0.001*

  1. MDR: multifactor dimensionality reduction; Bal.Acc: balanced accuracy; CVC: cross-validation consistency; OR: odds ratio; 95%CI: 95% confidence interval; Bold type *p < 0.05 indicates statistical significance
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BMC Medical Genomics

ISSN: 1755-8794

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