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Fig. 5 | BMC Medical Genomics

Fig. 5

From: Screening of core genes prognostic for sepsis and construction of a ceRNA regulatory network

Fig. 5

Meta-analysis. (A-D) Meta-analysis for expression of CD247, IL-1R2, IL-2Rβ and TGF-βR3 in the sepsis group versus the normal group in GSE28750, GSE54514, GSE69528, GSE95233 and GSE67652 datasets. IL-1R2 was up-regulated, while IL-2Rβ and TGF-βR3 were down-regulated in sepsis; CD247 marginally varied between the two groups. (E-H) Meta-analysis for expression of CD247, IL-1R2, IL-2Rβ and TGF-βR3 in the sepsis group versus the SIRS group in GSE28750, GSE6535, GSE63042, GSE74224 and GSE12624 datasets. CD247, IL-2Rβ and TGF-βR3 were down-regulated in sepsis versus SIRS and IL-1R2 marginally varied between the two groups. A random-effects model was used when the heterogeneity P value was < 0.05, otherwise, a fixed-effects model was used

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