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Fig. 3 | BMC Medical Genomics

Fig. 3

From: Clinically relevant combined effect of polygenic background, rare pathogenic germline variants, and family history on colorectal cancer incidence

Fig. 3

Interplay of pathogenic variant carrier status, family history, and polygenic risk score in single genes. Odds ratios (ORs) for colorectal cancer (CRC) were estimated from logistic models adjusted for age, sex, CRC screening status, and first four ancestry principal components. Non-carriers with intermediate PRS and no family history served as the reference group

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BMC Medical Genomics

ISSN: 1755-8794

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