Inflammation and neuronal gene expression changes differ in early versus late chronic traumatic encephalopathy brain

Table 3 Counts of enriched GO terms grouped by high level category uniquely significant in CTE-L, in CTE-H, or implicated by both sample groups

Trend category	CTE-L	Both	CTE-H
Cytoskeleton	0	0	8
Apoptosis	0	0	17
Signaling	0	0	26
Neuron	1	1	5
Cell cycle	0	1	20
Development	0	1	22
Protein processing	0	1	45
BBB	0	2	4
ECM/membrane	0	2	32
Ion homeostasis	0	3	5
Other	0	3	6
Metabolism	1	3	23
Transcription/translation	0	9	16
Immune/inflammation	2	15	76

ECM and BBB stand for extracellular matrix and blood brain barrier, respectively.’other’ contains GO terms not easily grouped into the other categories. GO term categories used were found in Additional file 1: Table S1

ISSN: 1755-8794