Table 3 Genotype and allele distribution of rs34125392, rs4380143 and 1,800,437 in study population
Allele/Genotype | Control (n = 100) | T2DM (n = 100) | P value | |
|---|---|---|---|---|
rs34125392 | ||||
Allele | T | 97(48.5%) | 80(40%) | NS |
- | 103(51.5%) | 120(60%) | ||
Genotype | T/T | 27(27%) | 13(13%) | 0.043 |
T/- | 43(43%) | 54(54.9%) | ||
-/- | 30(30%) | 33(33%) | ||
T/- + -/- | 73 | 87 | 0.021 | |
rs4380143 | ||||
Allele | T | 110(55%) | 102(51%) | NS |
C | 90(45%) | 98(49%) | ||
Genotype | T/T | 23(23%) | 16(16%) | NS |
T/C | 65(65%) | 70(70%) | ||
C/C | 12(12%) | 14(14%) | ||
T/C + C/C | 77 | 84 | NS | |
rs1800437 | ||||
Allele | G | 154(23%) | 150(75%) | NS |
C | 46(77%) | 50(25%) | ||
Genotype | G/G | 7(7%) | 5(5%) | NS |
G/C | 32(32% | 40(40%) | ||
C/C | 61(61%) | 55(55%) | ||
G/C + C/C | 93 | 95 | NS | |