Table 2 The enriched terms of Gene ontology for ferroptosis-WGCNA genes

BP

GO:0007568

aging

7.92E-04

MTOR/ATG7/MAPK8/ATM/MAPK3

BP

GO:0000422

autophagy of mitochondrion

2.35E-03

HIF1A/ATG7/ATG13

BP

GO:0008366

axon ensheathment

3.99E-02

MTOR/LPIN1

BP

GO:0007569

cell aging

6.02E-03

MTOR/MAPK8/ATM

BP

GO:0036473

cell death in response to oxidative stress

2.63E-02

HIF1A/ATG7

BP

GO:0071347

cellular response to Interleukin-1

3.18E-02

HIF1A/MAPK3

BP

GO:0090398

cellular senescence

2.60E-02

MAPK8/ATM

BP

GO:0006631

fatty acid metabolic process

3.06E-02

MTOR/LPIN1/MAPK3

BP

GO:0007612

learning

4.27E-02

MTOR/HIF1A

BP

GO:0002260

lymphocyte homeostasis

1.69E-02

HIF1A/TNFAIP3

BP

GO:0016236

macroautophagy

2.90E-05

MTOR/HIF1A/ATG7/ATG13/MAPK8/MAPK3

BP

GO:0070997

neuron death

2.74E-02

MTOR/HIF1A/ATG7

BP

GO:0034250

positive regulation of cellular amide metabolic process

4.97E-02

MTOR/MAPK3

BP

GO:0010506

regulation of autophagy

3.60E-05

MTOR/HIF1A/ATG7/MAPK8/ATM/MAPK3

BP

GO:0001959

regulation of cytokine-mediated signaling pathway

4.58E-02

HIF1A/TNFAIP3

BP

GO:0035303

regulation of dephosphorylation

3.81E-02

MTOR/LPIN1

BP

GO:0051090

regulation of DNA-binding transcription factor activity

3.85E-02

MAPK8/TNFAIP3/MAPK3

BP

GO:0010821

regulation of mitochondrion organization

4.27E-02

HIF1A/MAPK8

BP

GO:0031644

regulation of nervous system process

4.27E-02

MTOR/LPIN1

BP

GO:1,903,203

regulation of oxidative stress-induced neuron death

7.98E-03

HIF1A/ATG7

BP

GO:0031396

regulation of protein ubiquitination

1.18E-02

MTOR/TNFAIP3/HERPUD1

BP

GO:0010038

response to metal ion

2.86E-02

HIF1A/MAPK8/MAPK3

BP

GO:0006979

response to oxidative stress

2.15E-04

HIF1A/ATG7/MAPK8/ABCC1/TNFAIP3/MAPK3

BP

GO:0000302

response to reactive oxygen species

2.11E-03

HIF1A/MAPK8/TNFAIP3/MAPK3

BP

GO:0061912

selective autophagy

1.95E-02

ATG13/MAPK3

BP

GO:0072331

signal transduction by p53 class mediator

9.24E-03

MTOR/CD44/ATM

BP

GO:0031929

TOR signaling

5.64E-03

MTOR/HIF1A/ATM

CC

GO:0000407

phagophore assembly site

2.29E-02

ATG7/ATG13

MF

GO:0004707

MAP kinase activity

5.86E-03

MAPK8/MAPK3

MF

GO:0106310

protein serine kinase activity

7.56E-03

MTOR/MAPK8/ATM/MAPK3

MF

GO:0004674

protein serine/threonine kinase activity

7.56E-03

MTOR/MAPK8/ATM/MAPK3