Fig. 6

Correlations between GaGs signature with clinical or biological characters in TGCA-THCA cohort, GEO datasets and PTC cell lines. (A-F) The distribution of the signature risk-scores according to different status of T stage, disease stage, lymph node metastasis, histological type, extrathyroidal invasion and progression status in the TCGA-THCA dataset. (G-I) The distribution of the signature risk-scores according to different type of tumor tissues from three external datasets. Papillary thyroid carcinoma (PTC), anaplastic thyroid carcinoma (ATC) and poorly differentiated thyroid carcinoma (PDTC). (J) Relative expression level of 11 Golgi signature genes to GAPDH (2^−ΔΔCT) in Nthy-ori 3.1 and KTC-1 cell line (n = 3). Data are presented as interleaved bar plot. Scale of left Y axis was presented as log 10 format. Unpaired t test or Mann-Whitney test, *P < 0.05 ***P < 0.001