Fig. 7

The immune landscape in IgAN and normal controls. (A) Principal components analyses (PCA) performed on all samples. (B) The difference in infiltrating immune cells between IgAN and the normal group. The IgAN group was illustrated in red color and the normal group was illustrated in blue color. (C) Correlation heatmap of all 22 immune cells. The size of the colored dots indicates the strength of the correlation. The red color stands for a positive correlation, while the blue color stands for a negative correlation. Darker color indicates a stronger correlation. *p < 0.05, **p < 0.01, ***p < 0.001. (D) Correlation heatmap between hub genes and immune cells infiltration. The color depth of the triangle below is positively correlated with the correlation coefficient. The red color indicates a negative correlation, while the blue color indicates a positive correlation. The color depth of the upper triangle indicates p value. *p < 0.05, **p < 0.01, ***p < 0.001