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Table 2 Number of differentially expressed genes that overlap for muscle samples sequenced with standard and CoolMPS reagents at MGI subjected to DGE analysis across different group comparisons

From: An observational human study investigating the effect of anabolic androgenic steroid use on the transcriptome of skeletal muscle and whole blood using RNA-Seq

Comparison

RP2-4 Visit 2 (n = 3) vs. Visit 1 (n = 3)

RT (n = 17) vs. C (n = 5)

RT-AS ≤ 2 (n = 15) vs. C (n = 5)

RT-AS ≥ 10 (n = 11) vs. C (n = 5)

RT-AS ≤ 2 (n = 15) vs. RT (n = 17)

RT-AS ≥ 10 (n = 11) vs. RT (n = 17)

RT-AS ≤ 2 (n = 15) vs. RT-AS ≥ 10 (n = 11)

Up/Down regulation

1

2

18

2

68

0

11

Up

0

1

20

0

37

0

6

Down

  1. Genes with a false discovery rate (FDR) < 0.05 and fold change of 1.2 were reported as differentially expressed. DGE: differential gene expression; UoB: University of Brighton; RP: Returning Participant; C: non-resistance trained control group; RT: Resistance Trained control group RT-AS ≤ 2: Resistance Trained participant who self-declared AAS exposure ceased ≤ 2 weeks before sampling; RT-AS ≥ 10: Resistance Trained participant who self-declared AAS exposure ceased ≥ 10 weeks before sampling
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BMC Medical Genomics

ISSN: 1755-8794

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