Fig. 6

Schematic diagram of arginine methylation sites (bold and underlined) and serine/threonine sites (red) phosphorylated by PKC-ɑ and GSK3 within the C-terminal extremity of desmoplakin (aa 2823–2871). The change introduced by the mutation of the proband p.(S2863fs) is depicted along with two other frameshift mutation that have been observed in this region