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Fig. 2 | BMC Medical Genomics

Fig. 2

From: Single-cell RNA sequencing reveals sexual diversity in the human bladder and its prospective impacts on bladder cancer and urinary tract infection

Fig. 2

Sex-related diversity of urothelial cells in the human bladder. (A) Bubble plot showing ten representative GO pathways in female urothelial cells. (B) Bubble plot showing ten representative GO pathways in male urothelial cells. (C) DEG analysis showing ribosome biogenesis-related genes upregulated in urothelial cells in male bladders. (D) SCENIC analysis showing the activity of the transcription factor MYC in urothelial cells of females and males. The depth of the red represents the degree of activity. (E) Boxplot showing enrichment scores of representative metabolic pathways in male and female urothelial cells. (F) Violin plots demonstrating three antimicrobial compounds are predominantly expressed in urothelial cells in males

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BMC Medical Genomics

ISSN: 1755-8794

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