Fig. 4

Females exhibit a higher expression of B-cell and T-cell activated signals. (A-B) GSEA showing that females exhibit higher expression of B-cell activated signals (A) and higher expression of T-cell activated signals (B) than that in males. The normalized enrichment scores (NES) and adjust P value (P_adj) were showed on enrichment plots. When NES > 0 and P_adj < 0.05, it indicates that this pathway is enriched in females. (C) Violin plots demonstrating that six immunoglobulin genes are predominantly expressed in the B cells of females