Fig. 4

Functional enrichment analysis of the prognostic model. A Heat map of differentially expressed genes between low-risk group and high-risk group in George dataset. B Functional enrichment analysis of GO terms for the differentially expressed genes between low-risk group and high-risk group in George dataset. Yellow stars indicate the terms associated with ribosomes, and red stars indicate the terms associated with mitochondria. C Functional enrichment analysis of KEGG for the differentially expressed genes between low-risk group and high-risk group in George dataset. Yellow stars indicate the terms associated with ribosomes, and red stars indicate the terms associated with mitochondria. D GSEA enrichment analysis of both George dataset and GSE60052 dataset shows that the apoptotic pathway is enriched in the low risk group