BMC Medical Genomics

Table 4 Correlation between baseline characteristic and circRNAs expression level in CAD patient group

From: Interaction between the expression of hsa_circRPRD1A and hsa_circHERPUD2 and classical coronary risk factors promotes the development of coronary artery disease

Parameters	hsa_circRPRD1A				hsa_circHERPUD2				hsa_circLMBR1				hsa_circDHTKD1
Parameters	r	p	β	p	r	p	β	p	r	p	β	p	r	p	β	p
Age (years)	-0.077	0.252	0.168	0.343	-0.025	0.699	-0.327	0.043*	-0.062	0.348	0.209	0.164	-0.035	0.622	-0.298	0.034*
BMI (kg/m2)	0.078	0.291	0.001	0.997	0.152	0.026*	0.217	0.077	-0.087	0.215	-0.032	0.782	0.205	0.006*	-0.056	0.603
SBP (mmHg)	-0.02	0.778	-0.070	0.660	-0.004	0.948	-0.061	0.678	-0.061	0.365	-0.115	0.395	-0.023	0.755	0.268	0.032*
DBP (mmHg)	0.035	0.623	0.115	0.516	-0.026	0.697	-0.141	0.391	-0.063	0.349	0.128	0.399	-0.051	0.479	-0.275	0.050
Total cholesterol (mmol/L)	-0.019	0.787	1.398	0.307	-0.016	0.809	-1.711	0.175	-0.024	0.722	-1.199	0.304	0.045	0.526	1.562	0.154
TG (mmol/L)	-0.029	0.682	-0.127	0.467	-0.024	0.713	0.205	0.203	-0.042	0.531	0.127	0.392	-0.003	0.969	-0.121	0.391
HDL-C (mmol/L)	-0.035	0.622	-0.280	0.330	0.041	0.529	0.388	0.142	0.212	0.001*	0.197	0.422	-0.037	0.601	-0.151	0.516
LDL-C (mmol/L)	0.053	0.445	-1.292	0.293	0.032	0.618	1.557	0.169	-0.069	0.299	1.016	0.332	0.098	0.167	-1.413	0.151
GLU (mmol/L)	-0.02	0.773	-0.185	0.176	0.185	0.004*	0.092	0.469	-0.041	0.542	0.054	0.643	0.094	0.186	-0.140	0.205
Lp (a) (mg/L)	-0.051	0.469	0.390	0.008*	-0.020	0.757	0.058	0.682	0.134	0.040*	-0.211	0.097	0.082	0.239	0.154	0.203
Gensini score	0.158	0.023*	-0.151	0.308	-0.050	0.439	0.227	0.096	0.113	0.088	0.220	0.078	0.042	0.555	-0.242	0.040*
EF (%)	-0.014	0.873	-0.095	0.478	0.011	0.884	-0.065	0.599	0.066	0.422	-0.009	0.939	0.032	0.709	0.001	0.995
hsa_circRPRD1A	NA	NA	NA	NA	0.394	< 0.001	0.085	0.514	0.139	0.069	0.094	0.429	0.156	0.046	-0.079	0.487
hsa_circHERPUD2	0.394	< 0.001 **	0.099	0.514	NA	NA	NA	NA	0.061	0.399	0.100	0.441	0.070	0.352	0.090	0.462
hsa_circLMBR1	0.139	0.069	0.130	0.429	0.061	0.399	0.117	0.441	NA	NA	NA	NA	0.115	0.118	0.564	< 0.001**
hsa_circDHTKD1	0.156	0.046*	0.121	0.487	0.070	0.352	0.119	0.462	0.115	0.118	0.631	< 0.001**	NA	NA	NA	NA

* P < 0.05, ** P < 0.001.BMI: body mass index, SBP: systolic blood pressure, DBP: diastolic blood pressure, CRP: C-reaction protein, TG: triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C: low-density lipoprotein cholesterol, GLU: fasting blood glucose, Lip (a): lipoprotein (a), EF: ejection fraction.

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