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Table 5 Univariate and multivariable logistic regression analyses of the circRNAs and environmental factors in CAD risk

From: Interaction between the expression of hsa_circRPRD1A and hsa_circHERPUD2 and classical coronary risk factors promotes the development of coronary artery disease

Factors

Univariate analysis

Model 1

Model 2

OR (95% CI)

p

OR (95% CI)

p

OR (95% CI)

p

hsa_circRPRD1A

0.625(0.412–0.948)

0.027

0.628(0.404-0977)

0.039

0.613(0.380–0.987)

0.044

hsa_circHERPUD2

0.965(0.686–1.356)

0.837

0.946(0.640–1.399)

0.783

0.883(0.578–1.348)

0.565

hsa_circLMBR1

0.979(0.945–1.014)

0.229

0.983(0.947–1.021)

0.384

0.989(0.949–1.030)

0.989

hsa_circDHTKD1

1.069(0.902–1.266)

0.441

1.072(0.887–1.296)

0.471

1.096(0.891–1.348)

0.384

  1. Multivariate logistic regression Model 1: Adjusted for age, gender, BMI, smoking, drinking, diabetes mellitus and hypertension
  2. Multivariate logistic regression Model 2: Adjusted for age, gender, BMI, smoking, drinking, diabetes mellitus, hypertension, TC, TG, Apo(a), and LDL-C.
  3. OR: odds ratio, CI: confidence interval, TC: Total cholesterol, TG: triglyceride, Apo(a): apolipoprotein a, LDL-C: low-density lipoprotein cholesterol