Table 7 Interaction between circRNA and classical coronary risk factors of CAD.

hsa_circRPRD1A

hsa_circHERPUD2

Smoking

Smoking

-

-

65

2

1.000

-

-

56

2

+

-

43

11

0.631(0.085–4.654)

0.651

+

-

66

13

0.696(0.094–5.157)

0.723

-

+

41

2

0.120(0.025–0.570)

0.008

-

+

39

2

0.181(0.039–0.838)

0.029

+

+

29

5

0.178(0.033–0.974)

0.047

+

+

46

7

0.235(0.046–1.185)

0.079

 S (95%CI) = 0.658(-0.727-2.042) API (95%CI) = 2.395(-0.834-5.624)

RERI (95%CI) = 0.428(-1.210-2.065)

S (95%CI) = 0.682(-1.111-2.474) API (95%CI) = 1.521(-0.405-3.447)

RERI (95%CI) = 0.357(-1.555-2.270)

Drinking

Drinking

-

-

79

3

1.000

-

-

66

2

+

-

51

13

1.025(0.102–10.278)

0.983

+

-

82

17

0.439(0.059–3.273)

0.422

-

+

27

1

0.149(0.040–0.549)

0.004

-

+

29

2

0.146(0.033–0.655)

0.012

+

+

20

3

0.253(0.047–1.350)

0.108

+

+

29

3

0.293(0.046–1.848)

0.191

 S (95%CI) = 0.905(-2.546-4.355) API (95%CI) = 0.311(-0.605-1.228)

RERI (95%CI) = 0.079(-2.752-2.910)

S (95% CI ) = 0.500(0.218–0.782) API (95% CI ) = 4.415(1.230–7.599)

RERI (95% CI ) = 0.707(0.315–1.099)

Hypertension

Hypertension

-

-

34

2

-

-

35

3

+

-

28

8

2.118(0.286–15.678)

0.463

+

-

42

9

5.143(0.515–51.36)

0.163

-

+

72

2

0.206(0.040–1.049)

0.057

-

+

60

1

0.400(0.100-1.592)

0.194

+

+

43

8

0.316(0.063–1.587)

0.162

+

+

69

11

0.538(0.141–2.053)

0.364

 S (95%CI) =-2.117(-16.124-11.890) API (95%CI) = -3.182(-9.144-2.779)

RERI (95%CI) =-1.007(-5.935-3.922)

S (95%CI) =-0.130(-3.330-3.069) API (95%CI) =-7.457(-19.505-4.590)

RERI (95%CI) =-4.008(-17.065-9.050)