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Fig. 7 | BMC Medical Genomics

Fig. 7

From: Intronic position +9 and −9 are potentially splicing sites boundary from intronic variants analysis of whole exome sequencing data

Fig. 7

Statistical differences of the raw/pass/deleterious intronic variants number at different positions. a The statistical differences of raw intronic variant number at different positions. The P-value of t-test decreases with distance away from exons when the variants were at the intronic regions flanking exons between 20 and 150 bp, about half of them was significant difference (p < 0.01). The distance between which the variants number was significant difference was basically more and more small with the position away from nearby exons was more and more far. If the region were within 20 bp or more than 150 bp from nearby exon, the variants number at different position in these regions was always significant difference (p < 0.01). b The statistical differences of raw intronic variants FP at different positions. The proportion of false variants was non-significant difference (p > 0.05) between most positions. c The statistical differences of pass intronic variants number at different position. The number of pass variants was non-significant difference (p > 0.05) between most positions. d The statistical differences of deleterious intronic variant number at different positions. The number of deleterious variants was significant difference (p < 0.05) between some positions

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