Fig. 15
Somatic mutation analysis of Hub genes. A Mutation of hub genes in tumor samples. In the figure, the horizontal axis represents samples, and the vertical axis represents genes. The scale value on the right side of the picture refers to the percentage of samples with gene mutation in the total sample. The gray square indicates that the sample has not been mutated. Other colors are variant samples. The bar graph above the picture depicts the number and variant types of all variant genes in each sample, and the bar graph on the right side of the picture depicts the number of mutated samples in the current gene. The bar chart below the picture depicts the changes of the bases in each sample. B–I Scatter plots showed the correlation between hub genes and TMB. The x axis represents the log2TMB, and the y axis represents the expression value of each hub gene. “R” indicates the correlation coefficient value, and P value indicates the statistical significance