Fig. 2
From: Single-cell RNA-sequencing of stria vascularis cells in the adult Slc26a4-/- mouse
Cluster-defining genes of the stria vascularis cells, including canonical marker genes. A: Heatmap showing cluster-defining genes in intermediate cells (IMC), spindle cells (SC), root cells (RC), and marginal cells (MC) of the stria vascularis. Each cell group’s cluster-defining genes are ranked by ROC AUC score. B: The feature plot of each cell type show the expression of marker genes (IMC, Kcnj10; SC, Anxa1; RC, Epyc; MC, Kcnq1). C-F: Violin plots of the cluster-defining genes, including canonical marker genes. IMC (Dkk3, Spon1, Nrp2, Alpl); SC (Anxa1, Krt8, Anxa5, Wdc18); RC (Emb, Map1b, Fxyd6, Epyc); MC (Atp1b2, Kcnq1, Etnppl, Dnase1). The ROC AUC score of each gene is indicated under the name of the gene. G-J: Selected enriched Gene Ontology (GO) terms in the IMC (G), SC (H), RC (I), and MC (J). The melanosome, plasma membrane, membrane raft, and cell junction genes are enriched in the IMC; the SC expresses components of the extracellular exosome, the extracellular matrix is enriched in the RC, and the recycling endosome and Golgi apparatus are enriched in the MC (IMC, pink; SC, green; RC, cyan; MC, purple). The complete list of GO terms is available in supplementary tables S6-16