Table 3 Heterogeneity and pleiotropy evaluations for genetically causal associations of socioeconomic traits with FGP risk
Socioeconomic traits | nSNP | Heterogeneity | Pleiotropy | |||||
|---|---|---|---|---|---|---|---|---|
Q | I2 (%) | p | Intercept | SE | p | |||
Educational attainment | 320 | 293.38 | 8.7 | 0.845 | 0.002 | 0.004 | 0.647 | |
Job involves heavy manual or physical work | 15 | 8.887 | 57.5 | 0.838 | < 0.001 | 0.029 | 0.998 | |
Average total household income before tax | 32 | 47.818 | 35.2 | 0.027 | 0.001 | 0.023 | 0.975 | |
PPRESSO adjustment | 31 | 38.149 | 21.4 | 0.146 | 0.008 | 0.021 | 0.688 | |
Type of accommodation lived in: a flat, maisonette or apartment | 1 | NA | NA | NA | NA | NA | NA | |
Type of accommodation lived in: a house or bungalow | 1 | NA | NA | NA | NA | NA | NA | |
Townsend deprivation index at recruitment | 13 | 15.273 | 21.4 | 0.227 | 0.019 | 0.036 | 0.611 | |
Leisure/social activities: pub or social club | 10 | 21.437 | 58 | 0.011 | 0.007 | 0.043 | 0.871 | |
PPRESSO adjustment | 8 | 12.52 | 36.1 | 0.069 | 0.026 | 0.04 | 0.545 | |
Leisure/social activities: sports club or gym | 7 | 11.688 | 48.7 | 0.069 | 0.004 | 0.121 | 0.972 | |