Table 2 Univariate analyses of the clinicopathological characteristics associated with OS.

Pathological stage(III–IV vs. I–II )

2.053(1.229–3.341)

0.006

T stage (T3-T4 vs. T1-T2)

2.246 (1.072–4.706)

0.032

 N stage (N3-N4vs.N0-N1)

1.973 (1.026–3.795)

0.042

M stage (M1 vs. M0)

17.870 (5.597–57.051)

<0.001

Age, year ( ≧ 60vs.<60)

0.955 (0.500-1.824)

0.889

Sex (Female vs. Male)

1.262 (0.658–2.422)

0.484

Ulceration (No vs. Yes)

0.399 (0.207–0.768)

0.006

Clark level (I&II&III vs. IV&V)

0.304 (0.155–0.594)

0.001

Breslow depth (> 3 vs.≤3)

2.643 (1.310–5.334)

0.007

LSM2 expression (Low vs. High)

0.340 (0.171–0.677)

0.002