Fig. 1

A: Immunohistochemical findings. a & d: the tumor tissue showed high expression of estrogen and progesterone receptors (ER +  +  + , PR +  + +). b: immunohistochemical staining of p53 showed weak and heterogeneous staining, indicating a wild-type pattern. c: Ki67 was 25% positive. e: partial loss of expression of PTEN (+ +). e: clustered nuclear staining of β-catenin (+ + +) (200 ×). B: Immunohistochemical staining of mismatch repair proteins (a. MLH1, b. MSH2, c. MSH6, d. PMS2), all showing retention of nuclear staining (200 ×)