Fig. 7
The gene expression level in the datasets, advanced atherosclerosis cell model, and arterial tissue. A, B In the GSE23303 dataset, assessment of TRAF5 expression in smooth muscle cells and macrophage-enriched areas. C In the GSE21545 dataset, assessment of TRAF5 expression in death and survival cases. D, E In the GSE100927 and GSE49232 dataset, assessment of TRAF5 expression in carotid plaque and normal samples. F Validation of TRAF5 expression in the artery samples by RT-qPCR (n = 3). G, H Validation of TRAF5 expression in the artery samples by Western-blotting (n = 3, normalized to GAPDH). I The co-localization of TRAF5 and SM22 in ASO tissue. J Validation of TRAF5 expression in VSMCs treated with 100 mg/L oxidized-low density lipoprotein (n = 3). (*p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001)