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Fig. 1 | BMC Medical Genomics

Fig. 1

From: Evidence for causal effects of polycystic ovary syndrome on oxidative stress: a two-sample mendelian randomisation study

Fig. 1

Flow chart of the Two-sample MR study design. Step 1, A two-sample bidirectional Mendelian randomisation study for PCOS and 11 oxidative stress indices; Step 2, Some two-sample Mendelian randomisation studies for characteristics indices of PCOS and 11 oxidative stress indices. IVs, instrumental variables; PCOS, polycystic ovary syndrome; GST, glutathione S-transferase; CAT, catalase; SOD, superoxide dismutase; GPX, glutathione peroxidase; UA, uric acid; SNP, single nucleotide polymorphism;T, testosterone; LDL, low-density lipoprotein; HDL, high-density lipoprotein; SHBG, sex hormone-binding globulin; BMI, body mass index; TAG, triacylglycerol

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