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Table 1 Characteristics of the participants by CAD, T2D, and Obesity diagnosis. Coronary artery disease (CAD), type 2 diabetes (T2D), European (EUR), South Asian (SAS)

From: Assessing the performance of European-derived cardiometabolic polygenic risk scores in South-Asians and their interplay with family history

 

CAD

T2D

Obesity

Ethnicity

EUR

SAS

EUR

SAS

EUR

SAS

Diagnosis

Cases

Controls

Cases

Controls

Cases

Controls

Cases

Controls

Cases

Controls

Cases

Controls

Participants, N

24,156

428,610

822

7842

25,526

427,240

1718

6946

301,385

149,889

5690

2773

Male, N

(%)

18,514 (76.64)

188,835

(44.06)

690 (83.94)

3959 (50.48)

15,756 (61.73)

191,593 (44.84)

1055 (61.41)

3594 (51.74)

154,908 (51.39)

51,703 (34.49)

2993 (52.60)

1493 (53.84)

Female, N

(%)

5642 (23.36)

239,775 (55.94)

132 (16.06)

3883 (49.52)

9770 (38.27)

235,647 (55.16)

663 (38.59)

3352 (48.26)

146,477 (48.61)

98,186 (65.51)

2697 (47.40)

1280 (46.16)

Age, mean (SD)

61.51 (6.19)

56.53 (8.03)

58.71 (7.69)

53.05 (8.35)

60.39 (6.77)

56.58 (8.04)

57.42 (7.79)

52.64 (8.34)

55.73 (7.64)

56.81 (8.02)

53.8 (8.36)

53.1 (8.65)

Family history of CAD, N (%)

14,759 (61.1)

188,340 (43.94)

457 (55.6)

3193 (40.72)

13,131 (51.44)

189,968 (44.46)

754 (43.89)

2896 (41.69)

138,185 (45.84)

64,259 (42.87)

2411 (42.37)

1159 (41.79)

Family history of T2D, N (%)

5290 (21.9)

90,086 (21.02)

431 (52.43)

4144 (52.84)

10,120 (39.65)

85,256 (19.96)

1113 (64.78)

3462 (49.84)

68,794 (22.82)

26,267 (17.52)

3059 (53.76)

1430 (51.56)