Fig. 6From: The novel compound heterozygous variants identified in a Chinese family with glucose phosphate isomerase deficiency and pathogenicity analysisPredictive interactions of the wild-type and mutant sites of GPI protein. Residues in the wild-type and mutant sites are coloured light green and shown as sticks. The respective chemical interactions are labelled as dotted lines and coloured as follows: hydrogen bonds—red; weak hydrogen bonds—orange; hydrophobic contacts—green; amide-amide contacts—blue and ionic interactions—gold. Amino acid residues are also coloured according to type, namely nitrogen (blue), oxygen (red), and sulphur (yellow). Compared to the wild-type site, some interactions (hydrophobic, amide-amide, and ionic bonds) were observed to increase in the mutant siteBack to article page