Table 1 Clinical and echocardiographic findings of patients with cardiomyopathy

Male, n (%)

43 (59.7)

26 (63.4)

13 (52)

2 (100)

2 (50)

Familial, n (%)

35 (48.6)

26 (63.4)

8 (32)

0 (0)

1 (25)

Familial history of sudden death, n (%)

21 (29.2)

15 (36.6)

6 (24)

0 (0)

0 (0)

NYHA ≥ 3, n (%)

15 (20.8)

9 (21.9)

5 (20)

1 (50)

0 (0)

Median (IQR) age at diagnosis, years

29 (12–41)

30.1 (16–39)

16 (0–45.8)

60 (52–68)

7.6 (0–18.3)

Median (IQR) age at enrolment, years

34.5 (15.8–45)

36 (28–41)

20 (3.6–54)

61 (53–69)

13 (5.4–21.5)

Median (IQR) time from diagnosis to enrolment, years

3 (1–5)

3 (1–5)

2.9 (1.4–5)

1 (1–1)

2.45 (0.9–4.7)

Echocardiography

LVEF (%)

41.8 ± 21.26

30.73 ± 10.08

60.07 ± 23.01

39 ± 18.39

36.5 ± 19.13

LVEDD (mm)

48.4 ± 17.78

54.84 ± 16.25

38.82 ± 16.41

16.41 ± 48

44.8 ± 23.46

IVSd (mm)

10.16 ± 5.98

7.46 ± 2.0

14.91 ± 7.76

11 ± 1.41

7.13 ± 3.0

PWDd (mm)

8.03 ± 3.17

6.1 ± 3.27

8.43 ± 4.53

12.5 ± 0.71

6.6 ± 2.6

LV mass index (g/m²)

135.68 ± 124.09

108.15 ± 29.24

186.05 ± 93.94

111.5 ± 18.38

85.31 ± 24.97

Restrictive mitral pattern (%)

18 (25)

10 (24.4)

7 (28)

1 (50)

0 (0)

Mitral valve regurgitation ≥ moderate

21 (29.2)

15 (36.6)

6 (24)

1 (50)

0 (0)

Follow-up data

Anti-arrhythmic agent

9 (12.5)

4 (9.8)

5 (20)

0 (0)

0 (0)

P-M or ICD or CRT implantation

7 (9.7)

4 (9.8)

3 (12)

0 (0)

0 (0)

Any device (VAD or ECMO)

5 (6.9)

4 (9.8)

1 (4)

0 (0)

0 (0)

Heart transplantation

10 (13.9)

9 (22)

0 (0)

1 (50)

0 (0)

Mortality

8 (11.1)

4 (9.8)

3 (12)

0 (0)

1 (25)

Mean follow-up duration (years)

4.5

4.97

4.21

1

3.15