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Table 2 Top 10 genes selected from ceRNA network of characteristic miRNA by varElect

From: Identification of characteristic genes and construction of regulatory network in gallbladder carcinoma

Symbol

Description

type

Matched phenotypes

Matched phenotypes count

Score

Log10(p)

Average Disease Causing Likelihood

BRCA1

BRCA1 DNA Repair Associated

Protein

cancer

1

144.19

4.11

43.0

CHEK2

Checkpoint Kinase 2

Protein

cancer

1

81.58

3.37

42.5

RB1

RB Transcriptional Corepressor 1

Protein

gallbladder carcinoma, cancer

2

71.86

2.85

67.0

CASP8

Caspase 8

Protein

cancer

1

39.55

2.71

68.6

PTGS2

Prostaglandin-Endoperoxide Synthase 2

Protein

gallbladder carcinoma, cancer

2

28.05

2.05

66.5

CD44

CD44 Molecule (Indian Blood Group)

Protein

gallbladder carcinoma, cancer

2

22.23

1.86

34.3

KRT19

Keratin 19

Protein

gallbladder carcinoma, cancer

2

21.08

1.83

48.7

CDK1

Cyclin Dependent Kinase 1

Protein

gallbladder carcinoma, cancer

2

21.05

1.83

79.7

PVT1

Pvt1 Oncogene

ncRNA

gallbladder carcinoma, cancer

2

18.06

1.74

ND

MXRA5

Matrix Remodeling Associated 5

Protein

cancer

1

17.8

1.94

3.8